Round 1: Your goal here, regardless of draft position, is to get your consistent highlight reel player. More specifically, you want to grab a top 5 running back if available. Guys like Adrian Peterson, LeSean McCoy, Jamaal Charles, Matt Forte, and Eddie Lacy are must haves if you can get them. The only other viable running back options for the late half of the first round are MarShawn Lynch (who is a great risk because of being a hold out and getting less of a workload) and Monte Ball. Guys like Jimmy Graham, Calvin Johnson, Demaryius Thomas, or AJ Green are very solid first round picks. You can't go wrong with any of these top tier pass catchers.
Round 2: You are still looking at getting a running back, even if you already drafted one in the round prior. HOWEVER, NEVER OVERDRAFT A GUY LIKE ARIAN FOSTER. You are looking for a guy like Giovanni Bernard here. DO NOT take a quarterback unless Peyton Manning is available. You can get a Nick Foles or Tom Brady way later and stock up on your RBs and WRs. If you drafted a receiver in the first, you need to target a running back pretty much without a doubt here.
Round 3: Get your Wide Receiver here. Its plain and simple. More specifically get CORDARELLE PATTERSON or a guy like Antonio Brown. If you need a 2nd or even 1st running back then grab Andre Ellington if he is there.
Round 4: Receiver or Gronk/Cameron. You can get a Larry Fitz or a top tier tight end in the 4th round. If you do happen to miss on a top tight end then wait a couple rounds for someone, never overdraft a bad tight end.
Round 5: A Wide Receiver here should round out your main squad of point makers. By this point, in a perfect world, you will have 2 RBs and 3 WRs or 2 WRs and 1 TE. Get a receiver like Michael Floyd.
Round 6: Quarterback time! Get Nick Foles, Brady, RG3, or Kaepernick.
Round 7: Back up Running Back, get someone like Ben Tate to solidify your running back corps and put in the flex if your league has a flex position.
Round 8: Get Greg Olsen or Kyle Rudolph. You can get whatever tight end you want here but those two are my personal favorites.
Round 9: Get another Receiver or a top defense.
Round 10: Get a breakout sleeper like Zach Ertz or maybe even Johnny Manziel.